Found 24 matching trials
A Study of Imatinib Versus Nilotinib in Adult Patients With Newly Diagnosed Philadelphia Chromosome Positive (Ph+) Chronic Myelogenous Leukemia in Chronic Phase (CML-CP) PHASE3 In this study, the efficacy and safety of two nilotinib doses, 300 mg twice...
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University of California at Los Angeles Dept. of Hematology Clinic
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Study of Platelet Derived Growth Factor Receptor (PDGFR) in Recurrent Malignant Gliomas PHASE2 The purpose of this study is to determine the survival, disease response, a...
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The Rebecca and John Moores UCSD Cancer Center
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Nilotinib With Chemotherapy for the Treatment of Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia PHASE1 Patients with acute lymphoblastic leukemia and positivity for the breakpoin...
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Multiple Locations
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A Study of Imatinib and Nilotinib in Patients With Chronic Myelogenous Leukemia in Chronic Phase PHASE3 The extension study followed the core study CAMN107ECN02 (NCT01275196). whi...
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Novartis Investigative Site
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Nilotinib Pharmacokinetics (PK) in Gastrointestinal Stromal Tumor (GIST): Nilotinib PK N/A In patients who are receiving nilotinib, nilotinib plasma levels will be me...
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Asan Medical Center
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Nilotinib and Combination Chemotherapy in Treating Patients With Newly Diagnosed Acute Lymphoblastic Leukemia PHASE2 RATIONALE: Nilotinib may stop the growth of cancer cells by blocking some o...
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Daegu Fatima Hospital
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Study of Efficacy and Safety of Asciminib in Combination With Imatinib in Patients With Chronic Myeloid Leukemia in Chronic Phase (CML-CP) Who Have Been Previously Treated With Imatinib and Have Not Achieved Deep Molecular Response. PHASE2 To evaluate efficacy, safety and pharmacokinetic profile of asciminib 40mg+...
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Georgia Regents University
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Study of Tasigna®/Nilotinib (AMN107) in Neurofibromatosis (NF1) Patients With Plexiform Neurofibromas EARLY_PHASE1 The purpose of this Pilot Study is to determine if NF1 patients with plexif...
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Riley Hospital for Children
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Nilotinib Plus Dabrafenib/Trametinib or Encorafenib/Binimetinib in Metastatic Melanoma PHASE1 This is a phase 1 dose-escalation study of nilotinib in combination with fi...
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University of Iowa
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Efficacy and Safety Assessment of NIlotinib in CML Patients With Suboptimal Response on Imatinib Therapy PHASE4 whether Nilotinib at the two sequential dosage forms will induce quicker an...
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National Guard Hospital
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